1). Anadrol 50 has a lower affinity, which may be why we have a 50mg tablet dosage. When looking at the medical requirements, the recommended dosage for all ages has been 1 – 5 mg/kg of body weight. This would give a 220lb person a dosage as high as 10 Anadrol 50 tablets (500mg) per day.
There should be little wonder why when liver cancer has been linked to steroid use, Anadrol 50 is generally the culprit. Athletes actually never need such a high dosage and will take in the range of only 1-3 tablets per day.
It is interesting to note that oxymetholone does exhibit some tendency to convert to dihydrotestosterone in the body, although this does not occur via the 5-alpha reductase enzyme. Oxymetholone is already a dihydrotestosterone-based steroid, so no such alteration can take place. Aside from the added c-17 alpha alkylation (discussed below), oxymetholone differs from DHT only by the addition of a 2-hydroxymethylene group. This grouping can be removed metabolically, reducing oxymetholone to the potent androgen 17alpha-methyl dihydrotestosterone (mestanolone). 387 There is little doubt that this biotransformation contributes at least on some level to the androgenic nature of this steroid. Note that since 5-alpha reductase is not involved, the relative androgenicity of oxymetholone is not affected by the concurrent use of finasteride or dutasteride.
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