Anava (from "anu", meaning an atom or an exceedingly small entity) is a state - the consciousness of the ego, the sense of "I" and "mine". This represents a sense of individuality and a separation from a general existence of any "divine plan". One of the three Buddhist malas or bondages: anava, karma and maya . The three malas or pashas are also explicitly discussed in the theology of Shaivite Hinduism . In Shaivism , anava is the cause of the individual soul's mistaken sense of separate identity from Universal God Siva , and the last bond broken before union or Self-Realization ( moksha ).
The drug was prescribed to promote muscle regrowth in disorders which cause involuntary weight loss, and is used as part of treatment for HIV/AIDS . It had also been shown to be partially successful in treating cases of osteoporosis . However, in part due to bad publicity from its illicit use by bodybuilders , production of Anavar was discontinued by Searle Laboratories in 1989. It was picked up by Bio-Technology General Corporation, which changed its name to Savient Pharmaceuticals , which following successful clinical trials in 1995, released it under the tradename Oxandrin.  BTG subsequently won approvals for orphan drug status by the Food and Drug Administration for treating alcoholic hepatitis , Turner syndrome , and HIV-induced weight loss . It is also indicated as an offset to protein catabolism caused by long-term administration of corticosteroids .