Anava (from "anu", meaning an atom or an exceedingly small entity) is a state - the consciousness of the ego, the sense of "I" and "mine". This represents a sense of individuality and a separation from a general existence of any "divine plan". One of the three Buddhist malas or bondages: anava, karma and maya . The three malas or pashas are also explicitly discussed in the theology of Shaivite Hinduism . In Shaivism , anava is the cause of the individual soul's mistaken sense of separate identity from Universal God Siva , and the last bond broken before union or Self-Realization ( moksha ).

The drug was prescribed to promote muscle regrowth in disorders which cause involuntary weight loss, and is used as part of treatment for HIV/AIDS . It had also been shown to be partially successful in treating cases of osteoporosis . However, in part due to bad publicity from its illicit use by bodybuilders , production of Anavar was discontinued by Searle Laboratories in 1989. It was picked up by Bio-Technology General Corporation, which changed its name to Savient Pharmaceuticals , which following successful clinical trials in 1995, released it under the tradename Oxandrin. [19] BTG subsequently won approvals for orphan drug status by the Food and Drug Administration for treating alcoholic hepatitis , Turner syndrome , and HIV-induced weight loss . It is also indicated as an offset to protein catabolism caused by long-term administration of corticosteroids .