A meta-analysis was carried out to determine if there were scientific grounds for the use of hCG (human chorionic gonadotropin) for therapeutic purposes in the treatment of obesity. Studies relating to 8 controlled trials and 16 trials which were not uncontrolled which measured the effect hCG in therapeutic treatments of obesity were tracked down and researched. The tests were ranked in the quality of methods as well as key findings, authors, and data analysis and presentation regarding weight-loss, hunger, fat redistribution, and feelings of well-being. The methodological scores had varied from 16 to 73 points with a maximum of 100 possible points. This would indicate that most of the trials were of poor methodological outcomes. One report stated hCG as a use adjunct, scoring over 50 points. All of the studies scoring over 50 points were controlled studies. In conclusion, there is no scientific evidence that human chorionic gonadotropin is useful in treating obesity. It doesn’t reduce hunger or trigger any feelings of well-being.