Androgens like testosterone and DHT play a critical role in the pathogenesis of a number of dermatological conditions including acne , seborrhea , hirsutism (excessive facial/body hair growth in women), and pattern hair loss (androgenic alopecia).  In demonstration of this, women with complete androgen insensitivity syndrome (CAIS) do not produce sebum or develop acne and have little to no body , pubic , or axillary hair .   Moreover, men with congenital 5α-reductase type II deficiency , 5α-reductase being an enzyme that greatly potentiates the androgenic effects of testosterone in the skin, have little to no acne, scanty facial hair , reduced body hair, and reportedly no incidence of male pattern hair loss.      Conversely, hyperandrogenism in women, for instance due to PCOS or CAH , is commonly associated with acne and hirsutism as well as virilization (masculinization) in general.  In accordance with the preceding, antiandrogens have been found to be highly effective in the treatment of the aforementioned androgen-dependent skin and hair conditions.